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1.Pharmacokinetics, Part 1: Drug Administration, Absorption,
and Distribution4 Learning Credits

Part 1: An overview-style review of routes of administration, drug absorption and distribution, bioavailability and drug elimination, including the calculations you need to know and opportunities to practice using them. Visualize and actually understand drug elimination with clear graphs and concise explanations.
Lecturer: Mike McInnis, MD

2.Pharmacokinetics, Part 2: Drug Metabolism and Elimination4 Learning Credits

An expanded review of drug metabolism and elimination. Understand kinetics and test your understanding with clinically relevant practice questions.
Lecturer: Mike McInnis, MD

3.Drug-Receptor Interactions and Pharmacodynamics4 Learning Credits

Start with reviewing the chemistry of major receptor (G protein-coupled, ligand-gated ion channels, enzyme-linked, intracellular) families and ligands to understand how drugs cause effects.  Illustrations, animations, and tons of practice questions make learning easy and application to clinical practice clear.  Dose-response relationships are reviewed with clear graphic representations.
Lecturer: Mike McInnis, MD

4.Autonomic Nervous System4 Learning Credits

If you have a solid understanding of the autonomic nervous system, then learning the mechanism of action of many drugs will be much easier. The sympathetic and parasympathetic nervous systems are covered with a clinical twist. Learn this well now, and save yourself lots of study time moving forward!
Lecturer: Mike McInnis, MD

5.Cholinergic Agonists4 Learning Credits

Review the synthesis of acetylcholine and the diverse effects of cholinergic stimulation. Then explore the diverse uses of direct cholinergic agonists and cholinesterase inhibitors in diseases such as glaucoma, myasthenia gravis, asthma, and Alzheimer’s disease.
Lecturer: Mike McInnis, MD

6.Cholinergic Antagonists4 Learning Credits

Antimuscarinic drugs find their way into a broad range of clinical applications, including treatments for diarrhea and COPD, as well as various ophthalmologic uses. This lecture also covers neuromuscular blocking agents like rocuronium and succinylcholine, which are used by anesthesiologists for surgical paralysis.
Lecturer: Chris Lewis, MD

7.Adrenergic Agonists4 Learning Credits

From shock and acute asthma to the common cold, adrenergic agonists are used in a wide variety of clinical applications. After reviewing the synthesis of catecholamines and the functions of different types of adrenergic receptors, you’ll study the various applications of these drugs, as well as important pharmacokinetics and adverse effects.
Lecturer: Hujefa Vora, MD

8.Adrenergic Antagonists4 Learning Credits

In this lecture, you will review the effects of adrenergic stimulation and blockade, then discuss the specific alpha-antagonists used in the treatment of benign prostatic hypertrophy and hypertension, as well as the beta-blockers used in the management of hypertension, heart disease, and glaucoma.
Lecturer: Chris Lewis, MD

9.Neurodegenerative Disease Therapies4 Learning Credits

After reviewing the roles of various neurotransmitters in generating and inhibiting synaptic potentials, we review the pathophysiology of Parkinson’s Disease and discuss numerous strategies for managing this common disease. Treatments for Alzheimer’s Disease and Amyotrophic Lateral Sclerosis are also discussed.
Lecturer: Mike McInnis, MD

10.Anxiolytic and Hypnotic Drugs4 Learning Credits

Don’t be anxious! Learn the finer points of drugs used to treat a wide variety of anxiety disorders, such as benzodiazepines and buspirone. Dr. Lewis also discusses barbiturates and several drugs used to treat insomnia. Guaranteed not to put you to sleep!
Lecturer: Chris Lewis, MD

11.CNS Stimulants4 Learning Credits

Want to get stimulated? This lecture will go over the major stimulants, including caffeine, nicotine, cocaine, and amphetamines, as well as other psychotropic drugs such as LSD, PCP, and cannabinoids. Learn their mechanisms of action and their tendencies for addiction. Learn how to treat a cocaine overdose and be able to discern the difference between a PCP and an LSD intoxication.
Lecturer: Chris Lewis, MD

12.Anesthetics4 Learning Credits

Anesthesia is an important part of most medical procedures, from major surgery to suturing lacerations. This lecture explains the goals of anesthesia, the uses of inhaled, intravenous, and local anesthetics, and the potential side effects associated with the various drugs.
Lecturer: Cory Warmink, MD

13.Antidepressants4 Learning Credits

Following a brief overview of depression, mania, and bipolar disorders learn the therapeutic indications, mechanisms of action, adverse effects, and common interactions of SSRIs, SNRIs, atypical antidepressants, tricyclic antidepressants, and monoamine oxidase inhibitors.
Lecturer: Nanette Allison, DO

14.Neuroleptics4 Learning Credits

Learn the indications for neuroleptic drugs, including a foundational review of schizophrenia.  Focus on the mechanism of action and toxicities of the neuroleptic agents and review the medical strategies aimed toward alleviating such toxicities.  This lecture also explains the unique qualities of typical from atypical antipsychotics.
Lecturer: Chris Lewis, MD

15.Opioids4 Learning Credits

Understand the pathophysiology of pain and apply your understanding to the therapeutic options available for pain control.  The adverse effects of opioids will be explored in great detail.  You will have a chance to test your ability to choose the best opiate for a variety of clinical scenarios.
Lecturer: Chris Lewis, MD

16.Antiepileptics4 Learning Credits

Learn to classify seizures and then base your treatment choice on seizure classification and your understanding of the underlying pathophysiology of epilepsy. At the conclusion of this lecture you will confidently select the first line treatment for status epilepticus, absence, tonic-clonic and complex partial seizures.
Lecturer: Kevin Teal, MD

17.Heart Failure Drugs4 Learning Credits

A review of the physiology of heart failure, cardiac remodeling, and the body’s compensatory mechanisms, followed by an in-depth review of the six different classes of drugs used to manage CHF: inhibitors of renin-angiotensin system, beta-blockers, diuretics, vasodilators, inotropic drugs, and aldosterone antagonists.
Lecturer: Mike McInnis, MD

18.Antiarrhythmics4 Learning Credits

Learn the essential facts and characteristics of the four major classes of antiarrhythmic drugs. Learn which drug to use with which arrhythmia, and the major adverse reactions common with these very important medications. Though sometimes intimidating, the antiarrhythmic drugs are a cinch after this lecture.
Lecturer: Mike McInnis, MD

19.Antianginal Drugs4 Learning Credits

A not-so-painful review of the basics of the disease and the indications for treatment. Learn the details of the therapeutics and the clinical indications guiding therapy choice.
Lecturer: Mike McInnis, MD

20.Antihypertensives4 Learning Credits

An overview of the hypertension disease state and diagnostic criteria. A clinically-guided comprehensive review of antihypertensives focusing on clinical indications for therapeutic choice.
Lecturer: Mike McInnis, MD

21.Blood Drugs4 Learning Credits

Aspirin, heparin, and warfarin are just three of the common drugs used to treat thrombotic and hypercoagulable disorders discussed in this lecture. Encompassing everything from platelet aggregation to the coagulation cascade, Dr. Lewis makes this complex and imposing material very accessible. Also covered are thrombolytics, drugs used to treat excessive bleeding, and drugs used to treat various types of anemia.
Lecturer: Chris Lewis, MD

22.Lipid Drugs4 Learning Credits

Learn to base your treatment recommendations on the well defined national treatment guidelines for lipid goals based upon disease states and risk factors.  You will learn the therapeutic indications, side effects, and mechanisms of action of statins, niacin, fibrates, bile acid-binding resins, cholesterol absorption inhibitors and more.
Lecturer: Chris Lewis, MD

23.Diuretics4 Learning Credits

A rapid yet thorough review of nephron physiology tied to the mechanisms of action of the diuretics. Learn how and where each diuretic works and the clinical indications for the use of specific therapeutics.
Lecturer: Hujefa Vora, MD

24.Pituitary and Thyroid Therapies4 Learning Credits

Hormone therapies can be complicated, but we have you covered! Review the hypothalamic-pituitary axis from top to bottom, including all the natural and synthetic hormones and inhibitors. Plus, we outline the thyroid hormones and thyroid inhibitors that are commonly used in clinical practice.
Lecturer: Chris Lewis, MD

25.Insulin and Diabetes Mellitus4 Learning Credits

An overview of Diabetes Mellitus packed full of clinical connections. Review must-know facts about insulin and learn the real practice rules of thumb for insulin dosing and administration.
Lecturer: Mike McInnis, MD

26.Other Diabetes Drugs4 Learning Credits

After learning the pathophysiology of Diabetes Mellitus in the Insulin and Diabetes Mellitus lecture, learn about the other therapeutic options used commonly for type II DM patients.  Watch and learn the therapeutic uses, mechanism of action, and side effects of these therapeutic options.  There’s a lot to learn, but the DIT active learning principles will improve your retention!
Lecturer: Mike McInnis, MD

27.Estrogens and Hormone Replacement Therapy4 Learning Credits

Packed with clinical relevance and full of memorable and entertaining anecdotes—from the basics of estrogen to menopause, HRT, SERMs and anti-estrogens—we’re pretty sure you will have fun during this lecture!
Lecturer: Hampton Richards, MD

28.Progestins and Contraception4 Learning Credits

Review the high yield hormone synthesis cascade and then learn what you need to know about oral contraceptive therapy in about an hour. This lecture also covers progestin-only formulations, intrauterine devices, and antiprogestin therapy.
Lecturer: Hampton Richards, MD

29.Androgens and Antiandrogens4 Learning Credits

Review the regulation and function of testosterone, its clinical applications, and the adverse effects associated with testosterone use.  The use of various anti-androgen drugs for prostate cancer and benign prostatic hyperplasia is also discussed.
Lecturer: Dan French, MD

30.Adrenal Hormones4 Learning Credits

A review of adrenal gland physiology to help you understand—not just memorize— the high yield clinical conditions related to adrenal hormone hypersecretion and hyposecretion. Memory aids included to help you ace your exams and remember the high yield information when you are pimped during your clinical rotations.
Lecturer: Mike McInnis, MD

31.Respiratory System Drugs4 Learning Credits

Let us help you get the asthma classification table under control! Once you know the table, the therapeutic indications for asthma will be a breeze. Other high yield respiratory disease states—COPD, allergic rhinitis, cough—and treatments are also covered.
Lecturer: Anji Moore, MD

32.Gastrointestinal and Antiemetic Drugs4 Learning Credits

Don’t let Pharm give you heartburn! Review drugs used to treat a huge variety of GI disorders, including GERD and peptic ulcer disease, nausea and vomiting, diarrhea, constipation, and irritable bowel syndrome.
Lecturer: Chris Lewis, MD

33.Other Therapies (Sexual Dysfunction, Bones, Obesity)4 Learning Credits

This lecture covers the various drugs used to some of the most prevalent diseases in our aging society: erectile dysfunction, osteoporosis and osteopenia, and obesity. With new drugs for these indications entering the market frequently, and others being withdrawn for safety issues, staying up to date can be challenging. Don’t be left behind!
Lecturer: Hampton Richards, MD

34.Principles of Antimicrobial Therapy4 Learning Credits

Learn the bacterial factors and patient factors that influence antimicrobial agent choice and develop a strong foundation that will allow you to prescribe with confidence.  Explore the antimicrobial drugs and their spectra, drug resistance, and combination therapy.  Start with this lecture, and then move on to the individual antibiotic class lectures. 
Lecturer: Anji Moore, MD

35.Cell Wall Inhibitors, Part 1: Penicillins4 Learning Credits

This lecture covers a general overview of penicillins, as well as the specifics regarding their mechanisms of action, mechanisms of resistance, therapeutic uses, and unique toxicities.  The mechanism and therapeutic use of beta-lactamase inhibitors is also reviewed.  After watching this lecture, you will know which antibiotic is indicated for the most common bacterial infections seen in clinical practice.
Lecturer: Jennifer Shuford, MD

36.Cell Wall Inhibitors, Part 24 Learning Credits

Dr. Shuford discusses all of the non-penicillin beta-lactam antibiotics, including cephalosporins, carbapenems, and monobactams, and non-beta-lactam cell wall inhibitors, including vancomycin, daptomycin, and bacitracin. These drugs are used to treat a broad spectrum of illnesses, from relatively minor conditions to life-threatening infections.
Lecturer: Jennifer Shuford, MD

37.Protein Synthesis Inhibitors4 Learning Credits

Tetracyclines, glycylcyclines, aminoglycosides, macrolides, and more! This lecture covers a ton of high yield material for exams and clinical practice. Discover which pieces of information you need to memorize and let us help you get the job done—this lecture is packed with memory aids.
Lecturer: Chris Lewis, MD

38.Quinolones, Folic Acid Antagonists, Urinary Tract Antiseptics4 Learning Credits

From community-acquired pneumonia and diverticulitis to simple UTIs, fluoroquinolones continue to be go-to antibiotics for a growing variety of common infectious diseases. Learn which quinolones are used for which infections, and why. TMP-SMX is also covered in detail, as is an assortment of drugs used to treat urinary infections.
Lecturer: Chris Lewis, MD

39.Antimycobacterials4 Learning Credits

An in-depth review of Mycobacterium tuberculosis and M. leprae and the associated treatment guidelines, including lots of clinically relevant practice questions focusing on high yield points.
Lecturer: Jennifer Shuford, MD

40.Antifungal Drugs4 Learning Credits

This lecture will arm you with the knowledge you need to control fungal infections!  Learn the therapeutic indications, mechanisms of action, and toxicities associated with commonly prescribed antifungal agents.  Gain clinical application experience related to cutaneous and systemic mycoses.
Lecturer: Jennifer Shuford, MD

41.Antiprotozoal Drugs4 Learning Credits

Learn the high yield protozoal infections and their treatment.  This lecture also offers a special focus on malaria.  A “must see” video before your next big exam or your next big trip!
Lecturer: Jennifer Shuford, MD

42.Anthelmintic Drugs4 Learning Credits

Nematodes, trematodes and cestodes—oh my!  Learn the mechanisms of action, indications, and adverse effects of the drugs that treat these wriggly threats.  You will differentiate the common from uncommon infections and direct your study to the high-yield infections and therapeutics.
Lecturer: Jennifer Shuford, MD

43.Antiviral Drugs, Part 14 Learning Credits

It used to be that viral illnesses were rarely treated with pharmacotherapy, but not anymore! From Acyclovir to Zanamivir, we’ve got you covered on everything you need to know about the antiviral drugs used to treat herpesviruses, viral hepatitis, and influenza.
Lecturer: Jennifer Shuford, MD

44.Antiviral Drugs, Part 2: HIV/AIDS Antiviral Drugs4 Learning Credits

Everything you need to know about protease inhibitors, entry inhibitors, integrase inhibitors, NRTIs and NNRTIs. Focus on HAART and practice answering clinically relevant and high yield study questions.
Lecturer: Jennifer Shuford, MD

45.Antineoplastics, Part 14 Learning Credits

Intimidated by anticancer drugs? After this lecture you won’t be. Learn the essentials of chemotherapy, including the major mechanisms of action of the most widely used anticancer drugs. Become familiar with the most common side effects of these medications. Know which drugs are used for which types of cancer.
Lecturer: Chris Lewis, MD

46.Antineoplastics, Part 24 Learning Credits

Dr Lewis continues his review of anticancer drugs, focusing on alkylating agents, microtubule inhibitors, hormone-based therapies, monoclonal antibodies, and many more.
Lecturer: Chris Lewis, MD

47.Immunosuppressants4 Learning Credits

As kidney, liver, and other organ transplants become more common, the use of immunosuppressant drugs is becoming more important, and more complex. After a brief review of the immune system, Dr. Lewis discusses the major classes of immunosuppressants: cytokine inhibitors, antimetabolites, and monoclonal antibodies. Let Solid Pharmacology help make a complicated topic less daunting!
Lecturer: Chris Lewis, MD

48.Anti-Inflammatory Drugs, Part 14 Learning Credits

Dive into the mechanisms of action of prostaglandins, NSAIDs, and acetaminophen and relate the mechanisms to the therapeutic indications.  Know which anti-inflammatory is indicated for specific patients with unique presentations.  You will also learn the important adverse effects associated with these drugs.
Lecturer: Hujefa Vora, MD

49.Anti-Inflammatory Drugs, Part 2: Antirheumatics and Gout Therapy4 Learning Credits

Explore the mechanisms of action and potential pitfalls of a wide variety of drugs used for rheumatologic diseases, including DMARDs, TNF inhibitors, and monoclonal antibodies. Also covered are specialized therapies for the treatment of hyperuricemia and gout.
Lecturer: Ashley Green, DO

50.Autacoids and Autacoid Antagonists4 Learning Credits

Medications that act upon autacoids receptors are among the most widely-used drugs, especially in OTC preparations for common conditions such as acid reflux, allergies, and the common cold. This lecture covers prostaglandins, H1-antihistamines, and H2-antihistamines, as well as serotonin-agonist triptans used to treat migraines, with a focus on adverse effects and potential drug-drug interactions.
Lecturer: Chris Lewis, MD

51.Toxicology4 Learning Credits

Learn the most common environmental and occupational toxins and antidotes from an emergency room physician’s entertaining perspective. This lecture also briefly touches on designer drugs of abuse.
Lecturer: Cory Warmink, MD

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